Breaking the Cycle of Bacterial Growth and Resistance
An Innovative Biotech Company in Boulder, CO.
Crestone is a Boulder, Colorado based clinical stage biopharmaceutical company developing new drug candidates with entirely novel mechanisms. Our research pipeline includes: C. diff treatment, antibiotic-resistant Gram-positive infection treatments, Tuberculosis treatments, and more.
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Who We Are
Boulder, Colorado-based Crestone, Inc. is a clinical stage biopharmaceutical company focused on inventing and developing novel mechanism of action small molecule drugs for serious bacterial infections. Our pipeline includes antibacterial agents aiming to treat a variety of serious conditions caused by antibacterial-resistant microbes, from C. difficile infection to MRSA, tuberculosis, and more.
Our Pipeline
Our R&D pipeline includes several programs that address areas of significant and growing unmet medical need, such as C. diff infection, all with novel mechanism of action agents.
Knowledge Portal

Presentation at ASM Microbe, Los Angeles, June 20, 2025: Microbiome Analysis of Fecal Samples Collected in a Phase 2 Clinical Trial Comparing CRS3123 Vs. Vancomycin to Treat C. difficile Infection
Crestone made an impact at the ASM Microbe 2025 conference in Los Angeles by presenting groundbreaking research on microbiome analysis.

Presentation at ASM Microbe, Los Angeles, June 20, 2025: Microbiome Analysis of Fecal Samples Collected in a Phase 2 Clinical Trial Comparing CRS3123 Vs. Vancomycin to Treat C. difficile Infection
Crestone made an impact at the ASM Microbe 2025 conference in Los Angeles by presenting groundbreaking research on microbiome analysis.
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Interested in helping further our research into novel antibacterial agents? We’d be thrilled to have your help, either as an investoror a team member.
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Find work in a team-oriented environment at one of the leading Colorado pharma companies.
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